Bufo spinosus is a large and robust toad with a snout-vent length of 58.6 - 112 mm in males and 65 - 180 mm in females. Its head is relatively broad, and the region between the eyes is either flat or slightly concave. The snout is short and rounded. The tympanum is subtly visible and rounded, and its diameter does not exceed half the eye. The parotoid glands are large, elongated, and divergent at the posterior end. The eyes are prominent with a horizontally oval pupil. The skin is warty on the back and granular on the underside. Its warts usually end in a keratinized tip, resulting in a spiny appearance, though not all individuals express this. These keratinized warts are especially prominent between the corner of the mouth and the parotoid. The fingers, of which the third is the longest, are short. No information is available on the relative finger lengths. There are two palmar tubercles on the hands. The hind limbs are webbed, and have a pair of metatarsal tubercles, with the internal metatarsal tubercle being larger than the external metatarsal tubercle. No information is available on the relative toe lengths. There is a pair of subarticular tubercles on the hands and the feet that may be fused in older adults.
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