By the late 2010s, the species numbered several thousand and had been returned to the wild by captive breeding programmes. It is no longer in immediate danger of extinction, but remains absent from most of its historical range. It is not to be confused with the aurochs (Bos primigenius), the extinct ancestor of domestic cattle, with which it once co-existed.
Besides humans, bison have few predators. In the 19th century, there were scattered reports of wolves, lions, tigers, and bears hunting bison. In the past, especially during the Middle Ages, humans commonly killed bison for their hide and meat. They used their horns to make drinking horns.
The Białowieża or lowland European bison was kept alive in captivity, and has since been reintroduced into several countries in Europe. In 1996, the International Union for Conservation of Nature classified the European bison as an endangered species, no longer extinct in the wild. Its status has improved since then, changing to vulnerable and later to near-threatened.
European bison were first scientifically described by Carl Linnaeus in 1758. Some later descriptions treat the European bison as conspecific with the American bison. Three subspecies of the European bison existed in the recent past, but only one, the nominate subspecies (B. b. bonasus), survives today. The ancestry and relationships of the wisent to fossil bison species remain controversial and disputed.
The European bison is one of the national animals of Poland and Belarus.


